Who’s working on cell and gene therapy manufacturing?
Cell and gene therapies are made in small batches, often one patient at a time, and the hard problems are in the making: viral vector yield and purity, expanding cells without losing their potency, and release testing fast enough for the patient waiting on the batch. This page shows how much of that work the Helikon Research Graph holds and gives you a problem statement to run in Partner Search.
What the Helikon Research Graph holds on cell and gene therapy manufacturing
2,400+
researchers
2,200+
publications
440+
U.S. patents
Counts from the Helikon Research Graph on 13 October 2026, rounded down. Each figure is counted on its own, so they aren’t added together.
How these were counted
- Publications: papers whose title, author names or research topics match the keyword set below, the same text the Literature search reads.
- U.S. patents: granted U.S. patents whose text matches the keyword set and that carry at least one of these CPC subclasses: C12N, C12M, A61K, C07K, G01N. That is the Patents search with the CPC subclass field set.
- Researchers: people in the graph who authored a matching publication or are named inventors on a matching patent.
- Keyword set:
"cell therapy manufacturing" OR "cell therapy production" OR "cell therapy bioprocessing" OR "cell therapy product" OR "gene therapy manufacturing" OR "gene therapy production" OR "viral vector manufacturing" OR "viral vector production" OR "viral vector purification" OR "AAV production" OR "AAV manufacturing" OR "AAV purification" OR "rAAV production" OR "adeno-associated virus production" OR "lentiviral vector production" OR "lentiviral vector manufacturing" OR "packaging cell line" OR "producer cell line" OR "empty capsids" OR "transduction efficiency" OR "CAR-T manufacturing" OR "CAR-T cell manufacturing" OR "stem cell manufacturing" OR "stem cell bioprocessing" OR "MSC manufacturing" OR "MSC expansion" OR "iPSC manufacturing" OR "ex vivo expansion" OR "CAR-T cell production" OR "CAR-T production" OR "AAV vector production" OR "AAV vector manufacturing" OR "lentivirus production" OR "lentiviral production" OR "retroviral vector production" OR "NK cell expansion" OR "mesenchymal stem cell expansion" OR "mesenchymal stromal cell expansion" OR "hematopoietic stem cell expansion"
Try it on a real problem
Partner Search ranks researchers against a problem statement by what their publications, patents and profiles say. This one’s ready to run. Edit it to fit your project.
Our AAV yields from transient transfection in suspension HEK293 cells fall as we scale up, and too many of the capsids come out empty. Looking for a group with upstream process development and empty and full capsid analytics.Run this in Partner Search
Who’s working on this
Bioengineering, chemical engineering, immunology and gene therapy groups at universities and medical schools, children’s and cancer hospitals that run their own cell processing and vector facilities, and company teams making vectors, cell therapies and the equipment and reagents to produce them. Many academic gene therapy programs hold the vector patents themselves.
Universities and research labs
Ranked by researchers with work in this area, researchers whose main topic it is, and the U.S. patents they own.
- University of Pennsylvania
24 researchers · 35 publications · 23 U.S. patents
- University of North Carolina at Chapel Hill
25 researchers · 18 publications · 13 U.S. patents
- University of Florida
15 researchers · 22 publications · 20 U.S. patents
- University of Minnesota
43 researchers · 38 publications
- Duke University
20 researchers · 22 publications · 8 U.S. patents
- Children's Hospital of Philadelphia
7 researchers · 14 publications · 7 U.S. patents
- University of Pittsburgh
25 researchers · 14 publications · 1 U.S. patent
- The University of Texas MD Anderson Cancer Center
18 researchers · 36 publications · 2 U.S. patents
Companies
Ranked by the U.S. patents they own in this area and the researchers who work on it.
- Pfizer
8 researchers · 9 publications · 5 U.S. patents
- Johnson & Johnson
3 researchers · 5 publications · 8 U.S. patents
- Thermo Fisher Scientific
6 researchers · 21 publications · 4 U.S. patents
- Biogen
8 researchers · 11 publications
- Sanofi · France
7 researchers · 4 publications · 15 U.S. patents
- Novartis · Switzerland
10 researchers · 16 publications · 14 U.S. patents
- Oxford BioMedica · United Kingdom
2 researchers · 14 publications · 10 U.S. patents
- Takeda · Japan
1 researcher · 19 publications · 3 U.S. patents
From the Helikon Research Graph on 13 October 2026. Researchers are people now at the organization who authored a matching publication or are named inventors on a matching patent. Publications are matching publications that list the organization among their authors’ affiliations at the time of publication, counted once each. Patents are matching U.S. patents the organization owns. Each name opens the organization’s page on Helikon Labs.
Related
More technology areas
- Additive manufacturing
- Energy storage
- Drug delivery
- Biomanufacturing
- PFAS detection and replacement
- Antimicrobial resistance
- Clean hydrogen
- Chemically recyclable plastics
- Separation membranes
- Semiconductor fab and packaging
- Carbon capture and conversion
- Solar cells
- Robotics
- Autonomous vehicles
- Coatings and adhesives
- Fuel cells
- Bio-based materials and renewable feedstocks